The effect of storage period on hemolysis levels in packed red cells (PRC) at the PMI blood transfusion unit in Bandung city
Main Article Content
Keywords
Hemolysis, Packed Red Cells, Storeage
Abstract
Introduction: The Blood Transfusion Unit of PMI Bandung City during January - May 2023 has processed blood components with a total of 150,118 bags. The Packed Red Cells (PRC) were the most consumed blood components, accounting for 43% of total consumption. To obtain quality PRC components, one of the factors that must be considered is the level of hemolysis. The longer the storage period of blood in PRC, the more hemolysis levels will change. This study aimed to examine the effect of the shelf life of PRC on hemolysis levels at PMI Bandung City.
Methods: A descriptive experimental design was chosen for this study. PRC samples were randomly selected and examined for hemoglobin and hemolysis levels within a time series at 15 and 28 days of storage (n=30 bags). Data were statistically analyzed using a simple regression test.
Result: There was a strong correlation between the storage period and hemolysis levels (Multiple R-value of 0.831). Moreover, a significant increase in hemolysis levels during storage of 15 and 28 days was also found from an ANOVA test (p < 0.05).
Conclusion: It can be concluded that there was a significant effect of the storage period on erythrocyte hemolysis levels.
References
2. Wardhana CA, Lestari AAW, Wande IN, Herawati S, Mahartini NN. Correlation between hemolysis index and storage period to potassium levels of Packed Red Cells in Sanglah General Hospital, Bali, Indonesia. Bali Med J. 2022;11(2):501–5. doi: https://doi.org/10.15562/bmj.v11i2.3604
3. Makroo RN, Raina V, Bhatia A, Gupta R, Majid A, Thakur UK, et al. Evaluation of the red cell hemolysis in packed red cells during processing and storage. Asian J Transfus Sci. 2011;5(1):15–7. doi: https://doi.org/10.4103%2F0973-6247.75970
4. Maharani E, Noviar G. Immunohematology and Blood Bank. Jakarta: Center for Health Human Resource Education; 2018.
5. Lestari AAW, Triyono T, Sukorini U. Quality of Stored Red Blood. Indones J Clin Pathol Med Lab. 2018;23(3):294–302. doi: https://doi.org/10.24293/ijcpml.v23i3.1209