Overview of the storage duration of the packed red cell, thrombocyte concentrate, and fresh frozen plasma in transfusion reactions at Ngoerah Hospital Denpasar
Main Article Content
Keywords
Fresh frozen plasma (FFP), packed red cells (PRC), storage duration, thrombocyte concentrate (TC), transfusion reactions
Abstract
Introduction: Blood transfusion services are an integral part of healthcare efforts aimed at curing diseases and restoring health. Each blood component requires specific storage conditions and durations to maintain its efficacy. Blood components that are foreign to the recipient may trigger transfusion reactions. Data on transfusion reactions in Indonesia remains limited. However, several studies have found a significant association between the storage duration of blood products and the incidence of transfusion reactions. This study aimed to provide a comprehensive overview of the storage duration of packed red cells (PRC), thrombocyte concentrate (TC), and fresh frozen plasma (FFP) in cases of transfusion reactions.
Methods: This research is a descriptive cross-sectional study utilizing data from medical records and transfusion reaction reports at Ngoerah Hospital, Denpasar, from 2022 to 2023.
Result: Transfusion reactions occurred in 0.18% of PRC, 0.13% of TC, and 0.28% of FFP transfusions. Among transfusion reactions related to PRC, 58.9% had a storage duration of 0–7 days, with allergic reactions being the most common (54.7%), followed by febrile non-hemolytic transfusion reactions (FNHTR) at 44.2%. For TC, transfusion reactions occurred in units stored for ≤2 days (56.7%) and >2 days (43.3%), with allergic reactions accounting for 66.7% of cases. In FFP transfusions, 71.4% of reactions occurred with a storage duration of ≤30 days and all reactions were allergic in nature.
Conclusion: Transfusion reactions occur more frequently with shorter storage duration in PRC, TC, and FFP components. This may be due to the infrequent use of blood products with longer storage durations.
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