Differences in Hemoglobin Levels Before and After Packed Red Cell (PRC) Component Transfusion from the Blood Transfusion Unit of the Indonesian Red Cross Banjar City in Patients with Chronic Kidney Disease (CKD) at Banjar Patroman Hospital
Main Article Content
Keywords
Hemoglobin, Packed Red Cell, Chronic Kidney Disease, Blood Transfusion, Anemia, Indonesia
Abstract
Background: Packed red cell (PRC) transfusion remains an important intervention for rapid hemoglobin correction in CKD patients with severe or symptomatic anemia. However, the hemoglobin response following PRC transfusion in CKD patients managed at regional hospitals in Indonesia has not been systematically documented. This study aims to describe and compare hemoglobin levels before and after PRC transfusion in CKD patients at Banjar Patroman Hospital, using PRC supplied by the Blood Transfusion Unit (BTU) of the Indonesian Red Cross Society (IRCS), Banjar City, West Java, Indonesia.
Methods: This was an analytical observational study using a retrospective pre-post comparison design based on medical record data. The study enrolled 60 CKD patients who received PRC transfusion at Banjar Patroman Hospital between January and May 2025. Total sampling was applied. Pre- and post-transfusion hemoglobin values were extracted from hospital medical records and laboratory documents. The Wilcoxon signed-rank test was used to compare paired pre- and post-transfusion hemoglobin values, with statistical significance set at p < 0.05.
Results: Of the 60 patients included, 36 (60.0%) were female, and 24 (40.0%) were male. The most common age group was 51–60 years (58.3%). Following PRC transfusion, 58 patients (96.7%) experienced an increase in hemoglobin level, while two patients (3.3%) experienced a decrease. The Wilcoxon signed-rank test demonstrated a statistically significant difference between pre- and post-transfusion hemoglobin levels (p < 0.001). Median hemoglobin increment and the number of PRC units transfused per patient are reported where available in the main text.
Conclusion: PRC transfusion was associated with a statistically significant increase in hemoglobin among CKD patients at Banjar Patroman Hospital. These findings support the role of PRC transfusion as a short-term hemoglobin correction strategy in selected CKD patients with anemia.
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